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What To Know About Taking Provera


Updated June 02, 2014

Provera's Uses:

This medication is used to induce a period in a woman who has irregular menstrual cycles. It's also used in post-menopausal women who are taking estrogen supplements.

How Provera Works:

Provera is a form of progesterone. Taking Provera simulates the end of the menstrual cycle, after ovulation when progesterone is normally high. The withdrawal of progesterone (once you stop the medication) is what causes your period to start.


Provera is available in 2.5, 5.0 and 10 milligram tablets. Many practitioners will prescribe 5mg or 10mg each day to induce a withdrawal bleed.


1 tablet once a day for 5, 7 or 10 days as determined by your doctor.

When Will I Get My Period?:

You will get your period within two weeks of finishing the medication, although many women do get their periods while still taking Provera.

Side Effects:

  • Change in menstrual bleeding or flow
  • Acne
  • Headache
  • Fatigue
  • Breast tenderness
If you note any of the following side effects, please contact your physician immediately:
  • Visual or speech change
  • Severe headache
  • Sudden difficulty breathing
  • Sudden and severe mood changes
  • Severe abdominal, chest or leg pain

Drug Interactions:

  • Certain anti-seizure medications
  • St. John’s Wort
  • Rifampin
Make sure to tell your doctor about any medications or herbal supplements you are taking.


Provera is contraindicated in pregnancy. Make sure to tell your physician if you think you may be pregnant. Sometimes your physician will require that you take either a blood or urine pregnancy test before taking this medication.


"Provera" From DrugsAZ.About.com accessed on 8 April 2009.

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