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What is Anti Mullerian Hormone or AMH?

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Updated June 10, 2012

Question: What is Anti Mullerian Hormone or AMH?
Answer:

What is AMH?

Anti Mullerian Hormone (AMH) or Mullerian Inhibiting Substance is a special protein released by cells that are involved with the growth of an egg follicle each month. AMH levels correlate with the number of antral follicles found on the ovary each month; the higher the antral follicle count, the higher the AMH levels. Because women with PCOS typically have high numbers of antral follicles, high AMH levels are often seen as well. Besides being used as a potential diagnostic marker for PCOS, AMH is now sometimes used as an indicator of ovarian reserve in older women.

How is AMH tested?

AMH can be tested through a regular blood test. Not every physician may offer this test, so check with the office beforehand. It can be drawn during any day of the menstrual cycle and is sent to a special lab for analysis. Additionally, most insurance companies do not cover the cost of AMH testing, so you will probably need to cover the cost on your own.

What are normal AMH levels?

Normal AMH levels range between 0.7ng/ml to 3.5ng/ml. Levels below 0.3ng/ml are considered low, and indicate that lower numbers of eggs are within the ovary and decreased fertility. Between 0.3ng/ml to 0.7ng/ml are borderline low. Levels between 3.5ng/ml to 5.0ng/ml are borderline high, while anything above 5.0sng/ml is a high value and can indicate PCOS.

Sources:

Anti Mullerian Hormone and Mullerian Inhibiting Substance. Repromedix. Updated February 2007. Accessed 20 August 2008 from http://www.repromedix.com/pdf/AMHbL17CF181.pdf.

Won Tesoriero, Heather. A New Measure in Fertility Testing. The Wall Street Journal. Printed 22 April 2008.

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