Definition: Acanthosis nigricans are patches of dark, thickened, velvety skin behind the neck, on the thighs, or on the vulva. This can be seen with obesity, PCOS, and other disorders associated with insulin resistance.
By Nicole Galan, RN, About.com Guide
Updated July 31, 2008
About.com Health's Disease and Condition content is reviewed by the Medical Review Board
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